The impact of a pharmacist’s intervention on the use of prophylactic antibiotics in orthopedic surgery in a hospital in China


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Medicine (Baltimore). December 30, 2021; 100 (52): e28458. doi: 10.1097 / MD.00000000000028458.


This study aimed to assess the impact of the intervention directed by a pharmacist on perioperative antibiotic prophylaxis by standardizing the intradermal skin test with cephalosporin in the orthopedic department. A pre- and post-intervention study was conducted with patients in the orthopedics department of Chao-Yang Hospital in Beijing. in China. The use of the intradermal skin test, perioperative antibacterial prophylaxis and the cost of care were compared between the pre-intervention population (admitted from 06/01/2018 to 08/31/2018) and the post-intervention population (admitted from 01/01/2019 to 03/31/2018 / 2019). Logistic regression and generalized linear regression were used to assess the impact of the intervention. 425 patients from the pre-intervention period and 448 patients from the post-intervention period were included in the study. After the implementation of the pharmacist intervention program, there was a decrease in the use of intradermal skin tests, from 95.8% to 16.5% (P

PMID: 34967386 | DOI: 10.1097 / MD.000000000028458


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