Risk factors for venous thromboembolism in children undergoing orthopedic surgery

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Orthopedics. 2: December 1-7, 2021. doi: 10.3928 / 01477447-20211124-06. Online ahead of print.

ABSTRACT

Venous thromboembolism (VTE) is a rare but very morbid and potentially preventable complication in children. This study aimed to characterize the incidence and risk factors for VTE in children undergoing orthopedic surgery. A retrospective analysis was performed using the National Surgical Quality Improvement Program in Pediatric Surgery (NSQIP-P) 2012 to 2017 database from the American College of Surgeons. Patient demographics, comorbidities, operative variables, and perioperative outcomes were compared between patients who developed and not VTE. A total of 81,490 pediatric patients who underwent orthopedic surgery were identified. Of these, the mean age ± standard deviation was 9.7 ± 4.8 years and 50.1% were males. Sixty patients (0.07%) developed a postoperative VTE. In multivariate regression, the demographic and surgical variables associated with VTE were ages 16 to 18 (P= .002; compared to 11 to 15 years), American Society of Anesthesiologists (ASA) Classes III and V (P= .003; compared to ASA classes I and II), preoperative blood transfusion (P<.001 arthrotomy>P<.001 and fracture of the femur>P<.001 postoperative adverse events occurring before vte were also assessed. controlling for patient-related factors independent risk included any>P<.001 major adverse events>P<.001 minor adverse events>P<.001 reoperation>P<.001 and readmission>P<.001 this study identified an incidence of vte in a population over children undergoing orthopedic surgery. identification risk factors for patient raises the question prophylaxis certain high-risk subpopulations.>Orthopedics. 202x;xx(x):xx-xx.].

PMID: 34846239 | DOI: 10.3928 / 01477447-20211124-06


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